A woman stepping out of a sunlit doorway in the morning, market basket in hand

Weight · prescription telehealth

Hunger turned down. Weight coming off.

compounded semaglutide · weekly injection · prescription only

Compounded semaglutide for weight management: a once-weekly injection that quiets appetite and cravings so you feel satisfied on less, and supports steady, sustained weight loss. A licensed clinician decides whether it is appropriate for you, starts the dose low and steps it up only as you tolerate it — with notice before anything changes.

About eight minutes. A licensed clinician reviews every answer — and can say no.

Appetite

satisfied on less, so the diet stops being a fight

Dosing

steps up only as you tolerate it — your clinician's call

Price

every stage priced on this page, before you pay for month one

About Semaglutide

What semaglutide does, and what the first months are like.


What it does

Semaglutide mimics GLP-1, a gut hormone that slows stomach emptying and tells your brain you are full. A normal portion satisfies, cravings quieten, and the constant negotiation with food goes quiet with them. 1

How it's taken

One small injection under the skin, once a week, on the same day each week. Treatment starts at a low dose and steps up over several weeks as you tolerate it, on your clinician's direction — never on your own. 2

What to expect

Appetite usually changes within the first weeks; weight change builds over months and varies from person to person. In clinical trials of semaglutide for weight management, participants lost substantially more weight than those on placebo over more than a year. 3 Nausea is the most common early effect and usually eases as the dose settles. 2

The dose ladder: three stages — starting, building, full — each step only when the last was tolerated
What the intake asks and why: health history, medications and prior GLP-1 use, your state, goals and habits

How the dose moves

Your dose moves when your response does.

Semaglutide is not one dose. It is a ladder, and where you stand on it is a clinical decision made with you, week by week. 2


01

Starting

The first weeks are deliberately low — enough to let your body adjust, not enough to expect much on the scale yet. Mild nausea around the first doses is common and usually passes.

02

Building

If the last step was tolerated, your clinician raises the dose, typically every few weeks. Appetite quietens further; this is where most people notice the plate getting smaller on its own.

03

Full

The dose settles where it works for you and is held there. Not everyone reaches the top of the ladder, and no one is pushed up it.

04

Holding, or stepping down

A dose can be held at any stage — for side effects, for a plateau that is working, or because you and your clinician decide to come down. Nothing changes without notice.

Your price follows your stage, at the published rate for that stage. Every rung is on this page, under Plans & pricing.

The other routes

What you have probably already tried — and what each one cannot do.

Most people who start here have already done the hard part, more than once. Each of these routes can work for a while. Here is the thing each one cannot do that calibrated prescription care does.

What you have tried

Why it stalls

What calibrated care does

What you have tried

Willpower, counting, apps

Why it stalls

Appetite is biology. An app can count what you eat; it cannot change how hungry you feel at nine at night, or how loud food gets when you are tired.

What calibrated care does

Semaglutide acts on the appetite signal itself, so a smaller plate is enough and the counting stops running your day. 1

What you have tried

Fat burners and "GLP-1 booster" supplements

Why it stalls

Sold as supplements, so no one checked whether they work or what is in the capsule. None of them is a GLP-1 medication, whatever the label implies.

What calibrated care does

A prescription medication with a known mechanism, prepared for your prescription by a state-licensed U.S. pharmacy, prescribed by a clinician who has read your history.

What you have tried

Gym-only plans

Why it stalls

Training protects muscle, mood and the weight you keep off. On its own it rarely turns hunger down enough to move the scale for long.

What calibrated care does

Keep the training. Treatment lowers the intake side while you build the habits that hold the result.

What you have tried

Grey-market and "research-use" vials

Why it stalls

No prescription, no pharmacy license, no one checking the dose, the sterility or what is actually in the vial. 5

What calibrated care does

A state-licensed U.S. compounding pharmacy prepares your prescription and is named on your label. A licensed clinician sets every dose change.

What you have tried

One-size telehealth scripts

Why it stalls

A fixed script raises the dose on a calendar whether you tolerated the last step or not, and the price at month four is a surprise.

What calibrated care does

Your dose moves when your response does, with notice before anything changes and the option to hold. Every stage's price is published on this page.

Waiting it out is a route too. Weight that has held for years is not waiting for more resolve — and the intake takes eight minutes.

Not everyone gets the same dose. Why would you?

A principle of the house

How care works

Medicine, measured.

Results are personal, so treatment should not be one-size. Here is the whole process, plainly.


01

An intake worth reading

About eight minutes of real questions — your health history, medications, what you have tried, where your weight has been and where you want it. It is the basis of every decision that follows.

02

A clinician decides

A licensed U.S. clinician reviews your answers, may call you, and decides whether semaglutide is appropriate for you — and where your dose starts. Sometimes the answer is no. You will hear it straight.

03

Prepared and delivered

If prescribed, your medication is prepared for your prescription by a state-licensed U.S. compounding pharmacy — named on your label — and shipped in discreet, unmarked packaging.

04

Calibrated over time

The dose steps up only when you tolerate it. Your clinician moves it, you get notice before anything changes, and you can hold where clinically appropriate. Your price follows your stage, at the published rate.

The paperwork of care: an intake form, a fountain pen and a plain shipping box on a paper table

Plans & pricing

Every stage priced. Nothing to discover at month four.

Each plan includes the clinician evaluation, your medication, shipping and ongoing care. The first month is priced as an introduction; the standing price and every renewal term sit right beside it. What you see here is what you are agreeing to.

Monthly supply First month

Semaglutide Injection

$149 / first month

then $199/month from month 2 · cancel anytime

  • Compounded semaglutide, one small injection a week
  • Starts low; steps up only as you tolerate it, on your clinician's direction
  • Clinician evaluation, medication, shipping and ongoing care included
  • Prepared by a state-licensed U.S. compounding pharmacy, named on your label
  • Discreet, unmarked packaging; cancel anytime before your next billing date
  • Compounded medications are not FDA-approved
3-month supply

Semaglutide Injection

$529 / every 3 months

renews at $529 every 3 months · cancel anytime

  • Compounded semaglutide, one small injection a week
  • Starts low; steps up only as you tolerate it, on your clinician's direction
  • Clinician evaluation, medication, shipping and ongoing care included
  • Prepared by a state-licensed U.S. compounding pharmacy, named on your label
  • Discreet, unmarked packaging; cancel anytime before your next billing date
  • Compounded medications are not FDA-approved

The dose ladder · every rung priced

Semaglutide is priced by the stage you are on, not by the stage most people end up on. These are the standing prices for each stage, published before you pay for anything.

Stage Weekly dose Monthly Quarterly
Starting dosefirst month $149 0.22 / 0.44 mg $199 / month $529 / 3 months
Building dose 0.89 mg $239 / month
Full dose 1.5–2.5 mg $279 / month $749 / 3 months

Eligibility

See if it is appropriate. That is the consult.

Semaglutide is prescribed for weight management when your history and your numbers support it. A licensed clinician confirms eligibility during the assessment, and tells you plainly if it is not right for you.

You may qualify if

  • You are an adult aged 18 or over
  • Your BMI is 30 or higher — or 27 or higher with a weight-related condition such as high blood pressure, high cholesterol, pre-diabetes or sleep apnea
  • Diet and exercise on their own have not held
  • You are prepared to inject once a week and to keep a reduced-calorie plan alongside treatment
  • A clinician confirms it fits your health history

May not be suitable if

  • You are pregnant, breastfeeding or planning a pregnancy
  • You or a close relative have had medullary thyroid cancer, or you have Multiple Endocrine Neoplasia syndrome type 2
  • You have had pancreatitis, or gallbladder surgery in the last two months
  • You have or have had an eating disorder
  • You have had bariatric surgery in the last year
  • You have a severe gastrointestinal condition

Safety & honesty

What to expect, plainly.

Semaglutide has been studied in large trials and prescribed for years, so its effects are well described. Here is what is common, what is rare, and what rules it out. 2 3

Common, usually early, usually easing

  • Nausea — the most common effect, clustered around dose steps; smaller meals, eating slowly and a held dose are the usual fixes
  • Constipation or diarrhea — often in the first weeks; fluids and fiber help, and both tend to settle
  • Reflux, bloating, burping — stomach emptying is slower by design; heavy or fatty meals make it worse
  • Tiredness or headache — usually in the first weeks and usually mild

Stop and tell your clinician

  • Severe, persistent stomach pain — sometimes with vomiting — pancreatitis must be ruled out
  • Pain under the right ribs, fever or yellowing skin — signs of a gallbladder problem
  • A lump or swelling in the neck, hoarseness, trouble swallowing — semaglutide carries a boxed warning about thyroid C-cell tumors seen in rodents; it is not known whether this applies to people
  • Vomiting or diarrhea you cannot get on top of — dehydration can strain the kidneys
  • Shakiness, sweating, confusion — low blood sugar, mainly if you also take insulin or a sulfonylurea
  • Rash, swelling of the face or throat, trouble breathing — an allergic reaction — seek emergency care

Not prescribed if

  • You or a family member have had medullary thyroid cancer, or you have Multiple Endocrine Neoplasia syndrome type 2
  • You are pregnant, breastfeeding or planning a pregnancy — semaglutide is stopped at least two months before a planned pregnancy
  • You have had pancreatitis, an eating disorder, or bariatric surgery within the last year

Medicines that need care

Semaglutide slows stomach emptying, which can change how some oral medicines are absorbed, and it lowers blood sugar — so insulin and sulfonylureas may need adjusting. List everything you take in the intake, including supplements; your clinician checks each one before prescribing. 2

What it is for

Semaglutide is prescribed here for weight management in adults who meet the criteria above, alongside a reduced-calorie plan, when a licensed clinician decides it is appropriate. It is not a substitute for that plan, and it is not prescribed to anyone whose history rules it out.

If you stop

Appetite returns when semaglutide stops, and in the trial that followed people after it was withdrawn, most of the weight they had lost came back within a year. 4 That is why the dose here is calibrated over time rather than set once, and why stopping is a conversation with your clinician — a plan for holding or stepping down — rather than a cancelled card.

Compounded semaglutide is prepared for your prescription by a state-licensed U.S. compounding pharmacy, named on your label. It is not FDA-approved: compounded medications are not reviewed by the FDA for safety, effectiveness or quality. 6

Results vary. No outcome is guaranteed — your clinician will discuss what is realistic for you.

What happens next

From the intake to the first months on treatment.

Nothing here is a black box. This is the order things happen in, and what you will be holding at each point.


01

Today — the intake

About eight minutes: where you live, your health history, medications, what you have tried, your goals and habits, and whether you have used a GLP-1 before. Each question is there because it changes what is safe to prescribe.

02

Next — a clinician decides

A licensed U.S. clinician reviews every answer and may call you. They decide whether semaglutide is appropriate and where your dose starts. If you have been on a GLP-1 within the last two months, say so — you may be able to continue rather than restart.

03

Then — prepared and shipped

Your prescription goes to a state-licensed U.S. compounding pharmacy, which prepares it and ships it to you in discreet, unmarked packaging. The pharmacy is named on your label.

04

Week one — the starting dose

The first injection is a low dose on purpose. Appetite often changes within the first weeks; mild nausea around the first doses is common and usually passes. 2

05

Months one to four — stepping up

Your clinician raises the dose in steps, typically every few weeks, only when the last step was tolerated. You get notice before each change and the option to hold. Your price follows your stage, at the published rate. 2

06

From there — calibrated, not set

Refills continue at the dose that is working. Check-ins keep the plan honest, and if you and your clinician decide to hold, step down or stop, that is a plan too.

What arrives

The vial

One small glass vial of compounded semaglutide, prepared for your prescription

The label

The pharmacy's own label, with your name, your dose and the pharmacy's name on it

The box

Plain and unmarked outside, with the supplies to inject and your dosing directions inside

What arrives: a small glass vial and a folded cloth beside a plain kraft box on warm paper

Private

HIPAA-compliant platform · discreet, unmarked packaging

Clinician-led

licensed U.S. providers review every case

Your pharmacy

prepared by a state-licensed U.S. compounding pharmacy, named on your prescription label

Questions, answered plainly

Questions about semaglutide

What happens to my price when my dose goes up?

It moves to the published price for that stage — the dose ladder under Plans & pricing shows every stage. Your clinician decides the step, you get notice before your next billing, and you can hold at your current stage where clinically appropriate.

Who prepares my medication, and is it FDA-approved?

A state-licensed U.S. compounding pharmacy prepares it for your prescription and is named on your label. Compounded medications are not FDA-approved — they are not reviewed by the FDA for safety, effectiveness or quality. A licensed clinician decides whether one is appropriate for you before anything is prescribed. 6

I am already on a GLP-1 somewhere else. Do I have to start over?

Not necessarily. The intake asks when you last injected. If it has been within the last two months and you can show your current prescription, your clinician can decide to continue you at or near your current dose. After a gap of more than two months, treatment restarts at the starting dose — that is a safety rule, not a sales one.

Do I have to use needles?

Yes — one small injection under the skin once a week, with a short, fine needle like the ones used for insulin. Most people find the first one is the hard one. The pharmacy's directions cover how and where; your clinician is there for the rest.

What if it is not working?

Tell your clinician. Weight change builds over months, and during the first few the dose is usually still stepping up. If a step is not tolerated or a dose is not doing enough, your clinician adjusts it. If semaglutide is not right for you, they will say so — that is what the consult is for.

What if I want to stop?

Cancel anytime before your next billing date, from your account or by email; every cancellation is confirmed in writing, and medication already dispensed cannot be refunded. Talk to your clinician first: appetite returns when semaglutide stops, and in the trial that followed people after withdrawal most of the lost weight came back within a year, so stepping down is worth planning together. 4

What happens if I feel nauseous?

Nausea is the most common early effect and usually eases as the dose settles. Tell your clinician — holding the dose, adjusting timing or eating smaller meals often resolves it. Severe or persistent symptoms, especially stomach pain, are a reason to message your care team promptly.

How does the telemedicine process work?

You complete an online intake, a licensed provider reviews your case, and if appropriate your treatment plan is prescribed and delivered directly to your door.

Do I need to visit a doctor in person?

No. All consultations, prescriptions, and follow-ups are handled 100% online through our secure telehealth platform.

Are the doctors licensed?

Yes. Every provider in our network is licensed and experienced in evaluating patients through compliant telemedicine workflows.

Is my personal information secure?

Your information is protected through secure systems and privacy-first processes designed to support HIPAA-aligned care delivery.

How is my medication delivered?

Approved medications are shipped discreetly to your home, with updates and follow-up support handled online for convenience.

Sources

What this page is based on.

6 sources showhide

Every factual statement above comes from one of these. Nothing on this page is a promise about your result.

  1. Blundell J, et al. Effects of once-weekly semaglutide on appetite, energy intake, control of eating, food preference and body weight in subjects with obesity. Diabetes, Obesity and Metabolism, 2017. doi.org/10.1111/dom.12932
  2. FDA drug label (prescribing information) for the reference semaglutide injection for chronic weight management, 2025 revision: mechanism of action, dosage and administration, adverse reactions, warnings and precautions. accessdata.fda.gov/drugsatfda_docs/label/2025/215256s024lbl.pdf
  3. Wilding JPH, et al. Once-weekly semaglutide in adults with overweight or obesity (the STEP 1 trial). New England Journal of Medicine, 2021. doi.org/10.1056/NEJMoa2032183
  4. Wilding JPH, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: the STEP 1 trial extension. Diabetes, Obesity and Metabolism, 2022. doi.org/10.1111/dom.14725
  5. U.S. Food and Drug Administration. FDA's concerns with unapproved GLP-1 drugs used for weight loss. fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss
  6. U.S. Food and Drug Administration. Compounding and the FDA: questions and answers. fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers

The right level. The right dose. For you.

Start the intake — a licensed clinician will take it from there.